2021 Vol.2 Jun. No.2

• Title: Effect of telmisartan on arterial stiffness in elderly hypertensive patients
• Name: Iwakura Tomomi,Nitobe Inazo,Kenji Nomura
• Company: (Bangsong University,Hamamatsu 434-0027,Japan)
• Abstract:

   Purpose: To study the effect of telmisartan on arterial stiffness in elderly hypertensive patients. Method: Randomly select 100 elderly patients with hypertension from January 2022 to June 2022 as the research object. 100 patients were randomly divided into control group and experimental group by random number table. The control group was given routine calcium antagonist treatment, and the experimental group was given telmisartan 60mg/d. The blood pressure parameters, pulse conduction velocity (baPWV) and C-reactive protein (CRP) of the control group and the experimental group at 1 month, 3 months and 6 months after administration were statistically analyzed. Result: The diastolic blood pressure (DBP), systolic blood pressure (SBP) and pulse pressure difference (PP) of the patients in the experimental group were significantly lower than those in the experimental group (P<0.05), and the baPWV decreased by (368.3±262.57)cm/s after 6 months of administration. In addition, the improvement of CRP in the experimental group was better than that in the control group after treatment, and the difference between the two groups was statistically significant (P<0.05). Conclusion: Telmisartan can relieve the stiffness of large arteries in elderly patients with hypertension and increase the concentration of CRP, which can be widely used in clinical practice.

  
  

• Keyword: Telmisartan; Elderly patients with hypertension; Arterial stiffness; C-reactive protein concentration
• DOI: 10.12250/jpcarme2021010294
• Citation form: Iwakura Tomomi,Nitobe Inazo,Kenji Nomura.Effect of telmisartan on arterial stiffness in elderly hypertensive patients.2020, vol. 3,21-29.

[1]Xia Xiangmin, Li Dong. Effect of rosuvastatin combined with telmisartan on delaying cerebral white matter damage in elderly hypertensive patients[J]. Chronic Pathematology Journal, 2022, 23(08):1253-1255+1258.

[2]He Qianqian, Ambush, Zhang Zhaoting, et al. Characteristics of White Matter Lesions and Cerebral Hemodynamics in Patients with H Type Hypertension[J]. Chinese Journal of Stroke, 2020, 15(01):22-27.

[3]Yang Qunfei, Pan Quan. Effect of telmisartan on heart rate variability and heart rate turbulence in patients with essential hypertension[J]. China Modern Doctor, 2019, 57(20):30-33.

[4]Zhang Jin, Liu Yanling, Huang Shuangshuang. Effect of amlodipine combined with telmisartan on early renal damage in elderly patients with hypertension[J]. Guizhou Medical Journal, 2021, 45(12):1943-1944.

[5]Zhang Yu. Analysis of the effect of sulamlodipine+telmisartan in the treatment of hypertension and its impact on the quality of life of patients[J]. Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine(Electronic), 2020, 8(29):45+47.

[6]Qiao Hui, Wang Jingchun, Xin Yi. Clinical efficacy of valsartan and telmisartan in the treatment of elderly hypertension[J]. Modern Diagnosis & Treatment, 2020, 31(19):3043-3044.

[7]Deng Zhanbo. Clinical efficacy of telmisartan combined with levamlodipine in the treatment of elderly hypertension[J]. Modern Diagnosis and Treatment, 2019, 30(12):2025-2026.