location:Home > 2021 Vol.2 Mar.No1 > Correlation between hyperuricemia and cardiovascular and cerebrovascular diseases

2021 Vol.2 Mar.No1

  • Title: Correlation between hyperuricemia and cardiovascular and cerebrovascular diseases
  • Name: Masazo Tanaka1,Naoe Kanetsugu2
  • Company: (1.Tokyo Senkaku University,katsushika 125-0062,Japan; 2.West Kyushu University,Fukuoka 810-0042,Japan)
  • Abstract:

    Objective To investigate the correlation between hyperuricemia and risk factors of cardiovascular and cerebrovascular diseases. Methods The experimental group consisted of 107 patients with acute myocardial infarction, 57 males and 50 females, with an average age of (56.5 ± 5.5) years; There were 142 patients in the cerebral infarction group, 82 males and 60 females, with a mean age of (58.2 ± 4.5) years; There were 91 patients with cerebral hemorrhage, 51 males and 40 females, with an average age of (53.9 ± 9.5) years. The control group consisted of 146 inpatients in the same period without any evidence of cardiovascular and cerebrovascular diseases, including 80 males and 66 females, with an average age of (55.4 ± 11) years. There was no significant difference in average age among the groups (P>0.05). Results The levels of BMI, blood pressure, total cholesterol and triglyceride in patients with hyperuricemia were significantly higher than those in the control group; At the same time, cardiovascular and cerebrovascular diseases such as hypertension and coronary heart disease also have the characteristics of concentrated incidence, and the results of the control group were statistically significant (P<0.01). Conclusion Hyperuricemia has a clear relationship with the occurrence of cardiovascular and cerebrovascular diseases. Hyperuricemia, blood pressure, glucose and lipid metabolism disorders may jointly lead to the occurrence and development of cardiovascular and cerebrovascular diseases, and serum uric acid concentration is an important indicator representing the severity of CHD.


  • Keyword: Hyperuricemia; Cardio cerebrovascular diseases; BMI; Total cholesterol; miocardial infarction
  • DOI: 10.12250/jpcarme2021010166
  • Citation form: Toyotomi Hideyoshi,Xiaosu Zhongshun,Yoshimizu Takahiro.Study on the correlation between hyperuricemia and risk factors of cardiovascular and cerebrovascular diseases. 2020, vol. 3,1-4.
Reference:

[1]CHEN Lei , WU Chengkai , KANG Junming , LI Wenyuan . Association of Hyperuricemia with Common Chronic Diseases in Middle-aged and Older People over 45 Years in China. Chinese General Practice, 2021,24(4):447-452.

[2]LIU Weida , ZHANG Licheng , WANG Yong , LUO Yanxia . Incidence and Influencing Factors of Hyperuricemia in Hypertensive Populations. Chinese General Practice, 2019,22(34):4219-4224.

[3]YANG Lina , YANG Gangyi , PU Danlan . Research progress on relationship between changes in body compositions and risk of cardio-cerebrovascular diseases in patients with type 2 diabetes mellitus. Chongqing medicine, 2021,50(16):2831-2834,2838.

[4]LIU Qing , HUANG Zhe-zhou , GUO Yan-fei , RUAN Ye , SUN Shuang-yuan , SHI Yan , WU Fan . Association between cardiovascular and cerebrovascular diseases and cognition among Chinese aged 50 years and older. Chinese Journal of Disease Control & Prevention, 2021,25(3):295-299.

[5]TAN Qiang , JIAO Yan , ZHANG Rui-yuan , TANG Ping , KUANG Tao , HUANG Qiang , XIA Yin-yin , CHEN Li-shu . Analysis on causes of death and year of life lost among residents with cardio-cerebral vascular diseases in Chongqing,2011-2016. Chinese Journal of Health Education, 2020,36(2):108-111,120.

[6]Wu Qiutong , Ru Jinli , Li Xuxu . The adverse effects of low serum uric acid on patients with cardiovascular and cerebrovascular diseases. Chinese Journal of Endocrinology and Metabolism, 2022,38(3):253-255.


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